 | | Kaija Saariaho | Composer | Finnish composer | 1952 | |
 | | Eero Saarinen | Architect | Designed IBM's Watson Research Centre | 1910 | 1961 |
| |  | Albert Sabin | Biologist | Developed oral polio vaccine | 1906 | 1993 |
 | | Antonio Sacchini | Composer | Italian opera composer | 1730 | 1786 |
 | | Hans Sachs | Musician | Mastersinger | 1494 | 1576 |
 | | Vita Sackville-West | Poet | The Land | 1892 | 1962 |
 | | Anwar Sadat | Head of State | President of Egypt | 1918 | 1981 |
 | | Marquis de Sade | Author | 120 Days of Sodom | 1740 | 1814 |
 | | Morley Safer | Journalist | 60 Minutes | 1931 | |
| | | William Safire | Columnist | NYT columnist | 1929 | |
| | | Katey Sagal | Actor | Peg Bundy on Married With Children | 1954 | |
| | | Carl Sagan | Astronomer | Popular astronomer, host of Cosmos | 1934 | 1996 |
| | | Francoise Sagan | Novelist | | 1935 | 2004 |
| | | Carole Bayer Sager | Singer/Songwriter | | 1947 | |
| | | Bob Saget | Comic | America's Funniest Home Videos | 1956 | |
| | | Mort Sahl | Comic | Early influential stand-up comic | 1927 | |
| | | Edward Said | Author | Orientalism | 1935 | 2003 |
 | | Saint Basil | Saint | Defined three Persons in one Nature | 0329 | 0379 |
| | | Susan Saint James | Actor | McMillan and Wife | 1946 | |
| | | Antoine de Saint-Exupery | Author | The Little Prince | 1900 | 1944 |
| |  | Augustus Saint-Gaudens | Sculptor | Leading 19th c. American sculptor | 1848 | 1907 |
| |  | Yves Saint-Laurent | Fashion Designer | Christian Dior protege | 1936 | 2008 |
| | | Camille Saint-Saens | Composer | Samson et Dalila | 1835 | 1921 |
| | | Buffy Sainte-Marie | Musician | | 1941 | |
| | | George Saintsbury | Critic | A History of Criticism | 1845 | 1933 |
| | | Pat Sajak | Game Show Host | Wheel of Fortune | 1946 | |
 | | Kyu Sakamoto | Singer | Sukiyaki | 1941 | 1985 |
 | | Andrei Sakharov | Physicist | Developed the Soviet hydrogen bomb | 1921 | 1989 |
| |  | Saki | Novelist | Reginald | 1870 | 1916 |
 |  | Saladin | Royalty | Retook Jerusalem in 1187 | 1137 | 1193 |
| | | Ken Salazar | Politician | US Senator from Colorado | 1955 | |
| | | Theresa Saldana | Actor | Raging Bull | 1954 | |
| | | Soupy Sales | Comic | The Soupy Sales Show | 1926 | |
| | | Antonio Salieri | Composer | Italian composer | 1750 | 1825 |
| | | J. D. Salinger | Novelist | Catcher in the Rye | 1919 | |
| | | Jonas Salk | Doctor | Discoverer of the polio vaccine | 1914 | 1995 |
| | | Aulis Sallinen | Composer | Ratsumies (The Horseman) | 1935 | |
| | | Esa-Pekka Salonen | Conductor | | 1958 | |
| | | Carlos Salzedo | Composer | | 1885 | 1961 |
| | | Eric Salzman | Composer | American composer | 1933 | |
 | | Juan Antonio Samaranch | Sports Figure | Former Olympic Committee President | 1920 | |
| | | Richie Sambora | Guitarist | Bon Jovi | 1959 | |
| | | Giovanni Battista Sammartini | Composer | Formation of the symphony | 1700 | 1775 |
| | | Emma Samms | Actor | Fallon Carrington on Dynasty | 1960 | |
 | | Jorge Sampaio | Head of State | President of Portugal, 1996-2006 | 1939 | |
| | | Pete Sampras | Tennis | Fourteen Grand Slams | 1971 | |
| | | Will Sampson | Actor | One Flew Over the Cuckoo's Nest | 1933 | 1987 |
| | | Herbert Samuel | Politician | Anglo-Jewish politician and diplomat | 1870 | 1963 |
| | | Gar Samuelson | Drummer | | 1958 | 1999 |
 | | Chalino Sanchez | Singer | Prominent narcocorrido singer | 1960 | 1992 |
 | | Oscar Arias Sanchez | Head of State | Costa Rican President, 1986-90 | 1941 | |
| |  | Roselyn Sanchez | Actor | First hispanic in a US soap | 1973 | |
| | | George Sand | Novelist | | 1804 | 1876 |
| | | Carl Sandburg | Author | Lincoln biographer | 1878 | 1967 |
| | | Kurt Sanderling | Conductor | Leningrad Philharmonic Orchestra | 1912 | |
| | | Colonel Sanders | Chef | Kentucky Fried Chicken | 1890 | 1980 |
| | | Deion Sanders | Football | Played in both NFL and MLB | 1967 | |
| | | George Sanders | Actor | The Saint Strikes Back | 1906 | 1972 |
| | | Pharoah Sanders | Jazz Musician | The Creator Has A Master Plan | 1940 | |
| | | Richard Sanders | Actor | Les Nessman on WKRP in Cincinnati | 1940 | |
| | | Adam Sandler | Actor | The Wedding Singer, SNL alumnus | 1966 | |
| | | Isabel Sanford | Actor | Louise Jefferson on The Jeffersons | 1917 | 2004 |
| | | Terry Sanford | Politician | Governor and Senator from North Carolina | 1917 | 1998 |
 | | Samantha Sang | Singer | Emotion | 1953 | |
| | | Frederick Sanger | Chemist | Determined sequencing of Insulin | 1918 | |
| | | Margaret Sanger | Activist | Birth control advocate | 1879 | 1966 |
| | | Ira D. Sankey | Composer | The Sweet Singer of Methodism | 1940 | 1908 |
| | | Carlos Santana | Musician | Supernatural | 1947 | |
| | | George Santayana | Philosopher | The Realms of Being | 1863 | 1952 |
 | | Joey Santiago | Guitarist | Pixies | 1965 | |
| | | Ron Santo | Baseball | Third baseman, Chicago Cubs | 1940 | |
| | | Claudio Saracini | Composer | | 1586 | 1630 |
| | | Susan Sarandon | Actor | Louise in Thelma and Louise | 1946 | |
| | | Pablo de Sarasate | Composer | Spanish violinist and composer of the Romantic per | 1844 | 1908 |
| | | John Singer Sargent | Painter | American portraitist | 1856 | 1925 |
| | | Malcolm Sargent | Conductor | BBC Symphony Orchestra | 1895 | 1967 |
| | | David Sarnoff | Business | CEO of RCA, founder of NBC | 1891 | 1971 |
| | | William Saroyan | Author | The Time of Your Life | 1908 | 1981 |
| | | May Sarton | Poet | Plant Dreaming Deep | 1912 | 1995 |
| | | Jean-Paul Sartre | Philosopher | Nausea, No Exit | 1905 | 1980 |
| | | Jacqueline Sassard | Actor | Accident | 1940 | |
| | | Arthur E. Satherley | Country Musician | | 1889 | 1986 |
| | | Erik Satie | Composer | Messe des Pauvres | 1866 | 1925 |
| | | Joe Satriani | Guitarist | | 1956 | |
| | | Adam Savage | TV Personality | Host of MythBusters | 1967 | |
| | | Ben Savage | Actor | Cory on Boy Meets World | 1980 | |
| | | John Savage | Actor | The Deer Hunter | 1949 | |
| | | Jordi Savall | Composer | | 1941 | |
| | | Marilyn vos Savant | Columnist | IQ 228 | 1946 | |
| | | Wolfgang Sawallisch | Conductor | German conductor and pianist | 1923 | |
| | | Diane Sawyer | Journalist | TV news journalist | 1945 | |
| | | Gordon E. Sawyer | Musician | Sound for West Side Story | 1905 | 1980 |
| | | Robert J. Sawyer | Novelist | The Terminal Experiment | 1960 | |
 | | Adolphe Sax | Musician | Invented the saxophone | 1814 | 1894 |
| | | John Saxon | Actor | Enter the Dragon | 1936 | |
| | | Robert Saxon | Composer | | 1953 | |
| | | Dorothy L. Sayers | Novelist | Lord Peter Wimsey detective novels | 1893 | 1957 |
| | | Henry J. Sayers | Songwriter | | 0000 | |
| | | Alexei Sayle | Comic | Gorky Park | 1952 | |
| | | Boz Scaggs | Musician | | 1944 | |
| | | Antonin Scalia | Judge | US Supreme Court Justice | 1936 | |
| | | Alessandro Scarlatti | Composer | Mitridate Eupatore | 1660 | 1725 |
| | | Domenico Scarlatti | Composer | Composed 555 sonatas | 1685 | 1757 |
| | | Giacinto Scelsi | Composer | Italian composer | 1905 | 1988 |
| |  | Michael Schade | Singer | Canadian operatic tenor | 1965 | |
| | | Jack Schaefer | Novelist | Shane | 1907 | 1991 |
| | | Pierre Schaeffer | Electronic Musician | Inventor of musique concrčte | 1910 | 1995 |
| | | Rebecca Schaeffer | Actor | Actress murdered by stalker | 1967 | 1989 |
| | | Natalie Schafer | Actor | Mrs. Howell on Gilligan's Island | 1900 | 1991 |
| | | Lewis Schaffel | Sports Figure | Exec. VP of the New Jersey Nets | 9999 | |
| | | Paul Schaffer | Musician | David Letterman's bandleader | 1949 | |
 | | Zenna Schaffer | | Quotation | 0000 | |
| | | Philipp Scharwenka | Composer | Polish-German composer | 1847 | 1917 |
| | | Xaver Scharwenka | Composer | German pianist and composer. | 1850 | 1924 |
| | | Roy Scheider | Actor | Jaws | 1932 | 2008 |
| | | Samuel Scheidt | Composer | German composer, organist and teacher | 1587 | 1653 |
| | | Johann Schein | Composer | German composer of the early Baroque era | 1586 | 1630 |
| | | Maximilian Schell | Actor | Judgment at Nuremberg | 1930 | |
| | | Ernest Henry Schelling | Conductor | | 1876 | 1939 |
| | | Rudolf Schenker | Musician | The Scorpions | 1948 | |
| | | Hermann Scherchen | Conductor | | 1891 | 1966 |
| | | Kenneth Schermerhorn | Conductor | Nashville Symphony Orchestra | 1929 | 2005 |
| | | Elsa Schiaparelli | Fashion Designer | Parisian fashion designer | 1890 | 1973 |
| | | Vincent Schiavelli | Actor | Character actor and cookbook author | 1948 | 2005 |
| | | Peter Schickele | Composer | | 1935 | |
| |  | András Schiff | Pianist | Hungarian-born British classical pianist | 1953 | |
| | | Claudia Schiffer | Model | Top German supermodel | 1970 | |
| | | Friedrich Schiller | Playwright | Ode an die Freude | 1759 | 1805 |
| | | Baldur von Schirach | Government | Hitler-Jugend, Gauleiter of Vienna | 1907 | 1974 |
| | | Wally Schirra | Astronaut | Commander of Apollo 7 | 1923 | 2007 |
| | | Phyllis Schlafly | Activist | Opponent of women's liberation | 1924 | |
| | | Friedrich von Schlegel | Philosopher | Founder of the German Romantic movement | 1772 | 1829 |
| | | Friedrich Schleiermacher | Religion | A founder of Protestant theology | 1768 | 1834 |
| | | Arthur Schlesinger Jr. | Historian | The Age of Roosevelt | 1917 | 2007 |
| | | John Schlesinger | Film Director | Marathon Man | 1926 | 2003 |
| | | Laura Schlessinger | Radio Personality | The Dr. Laura Show | 1947 | |
| | | Arnolt Schlick | Composer | | 1460 | 1521 |
| | | Mary Schmich | Columnist | Brenda Starr | 0000 | |
| | | Franz Schmidt | Composer | Austrian composer, cellist and pianist | 1874 | 1939 |
| | | Florent Schmitt | Composer | French composer | 1870 | 1958 |
| |  | Artur Schnabel | Pianist | Pianist and classical composer | 1882 | 1951 |
| | | Fred Schneider | Singer | The B-52s | 1951 | |
| | | Rob Schneider | Actor | Deuce Bigalow: Male Gigolo | 1963 | |
| | | Romy Schneider | Actor | La Passante du Sans-Souci | 1938 | 1982 |
| | | Alfred Schnittke | Composer | Russian and Soviet composer | 1934 | 1998 |
| | | Gina Schock | Drummer | Drummer for The Go-Go's | 1957 | |
| | | Othmar Schoeck | Composer | Swiss composer | 1886 | 1957 |
| | | Arnold Schoenberg | Composer | Emancipated dissonance | 1874 | 1951 |
| | | Harold C. Schonberg | Critic | New York Times | 1915 | 2003 |
| | | Arthur Schopenhauer | Philosopher | Philosopher of Pessimism | 1788 | 1860 |
| | | Daniel Schorr | Journalist | Veteran journalist | 1916 | |
| | | Marge Schott | Baseball | Owner, Cincinnati Reds | 1928 | 2004 |
| | | Peter Schreier | Musician | | 1935 | |
 | | Olive Schreiner | Novelist | | 1855 | 1920 |
| | | Erwin Schrödinger | Physicist | Schrödinger's wave equation | 1887 | 1961 |
| | | Pat Schroeder | Politician | | 1940 | |
| | | Franz Schubert | Composer | Symphony No. 8, "Unfinished" | 1797 | 1828 |
 | | Erwin Schulhoff | Composer | | 1894 | 1942 |
| | | Gunther Schuller | Composer | Third Stream | 1925 | |
| | | Robert H. Schuller | Religion | Hour of Power | 1926 | |
| | | George Schultz | Government | U.S. Secretary of State | 1920 | |
| | | Charles Schulz | Cartoonist | Peanuts | 1922 | 2000 |
| | | Johann Abraham Peter Schulz | Composer | Ihr Kinderlein kommet | 1747 | 1800 |
| | | Klaus Schulze | Musician | Synthesizer pioneer | 1947 | |
| | | E. F. Schumacher | Economist | | 1911 | 1977 |
| | | William Schuman | Composer | Symphony No. 3 | 1910 | 1992 |
| | | Clara Schumann | Composer | Romantic pianist and composer | 1819 | 1896 |
| | | Robert Schumann | Composer | Toccata | 1810 | 1856 |
| | | Joseph Schumpeter | Economist | | 1883 | 1950 |
| | | Heinrich Schutz | Composer | Psalms of David | 1582 | 1672 |
| | | Arthur Schwartz | Songwriter | Dancing In The Dark | 1900 | 1984 |
| | | Delmore Schwartz | Poet | Delmore Schwartz | 1913 | 1966 |
| | | Jean Schwartz | Songwriter | Chinatown, My Chinatown | 1878 | 1956 |
| | | Gerard Schwarz | Conductor | | 1947 | |
| | | Arnold Schwarzenegger | Actor | Governor of California | 1947 | |
| | | Elisabeth Schwarzkopf | Singer | Soprano admired for her performances of Mozart, St | 1915 | 2006 |
| | | Norman Schwarzkopf | Military | United States Army general | 1934 | |
| | | Albert Schweitzer | Activist | Humanitarian and theologian | 1875 | 1965 |
| | | David Schwimmer | Actor | Dr. Ross Geller on Friends | 1966 | |
| | | Paul Scofield | Actor | A Man For All Seaons | 1922 | 2008 |
| | | Tracy Scoggins | Actor | Lochley on Babylon-5 | 1953 | |
| | | Peter Scolari | Actor | Bosom Buddies, Newhart | 1954 | |
| | | Martin Scorsese | Film Director | Taxi Driver | 1942 | |
| | | Bon Scott | Musician | AC/DC | 1946 | 1980 |
| | | Clement Scott | Songwriter | | 0000 | |
| | | Cyril Scott | Composer | English composer, writer, and poet | 1879 | 1970 |
| | | George C. Scott | Actor | Patton | 1927 | 1999 |
| | | Gordon Scott | Actor | Played Tarzan, 1955-60 | 1926 | 2007 |
| |  | Hazel Scott | Jazz Musician | Tico Tico | 1920 | 1981 |
| | | James Scott | Composer | Ragtime composer | 1885 | 1938 |
| | | John Scott | Musician | | 1956 | |
| | | Ken Scott | Engineer | | 1947 | |
| | | Linda Scott | Singer | I've Told Every Little Star | 1945 | |
| | | Raymond Scott | Musician | Inventor of the sequencer | 1908 | 1994 |
| | | Ridley Scott | Film Director | Alien | 1937 | |
| | | Robert Falcon Scott | Explorer | | 1868 | 1912 |
| | | Sir Walter Scott | Author | Ivanhoe | 1771 | 1832 |
| | | Willard Scott | TV Personality | Today Show weatherman, also world's first Ronald M | 1934 | |
| | | Zachary Scott | Actor | The Mask of Dimitrios | 1914 | 1965 |
| | | Alexander Scriabin | Composer | Prometheus: The Poem of Fire | 1872 | 1915 |
| | | John Sculley | Business | CEO of Apple, 1983-93 | 1939 | |
| | | Steven Seagal | Actor | Under Siege | 1951 | |
| | | Bobby Seale | Activist | Co-founder of the Black Panther Party | 1936 | |
| | | Humphrey Searle | Composer | British composer | 1915 | 1982 |
| | | John Sebastian | Singer/Songwriter | Theme to Welcome Back, Kotter | 1944 | |
| | | Jean Seberg | Actor | Saint Joan | 1938 | 1979 |
| | | Simon Sechter | Composer | 5,000 fugues, Bruckner's teacher | 1788 | 1867 |
| | | Charles de Secondat | Author | Theory of separation of powers | 1689 | 1755 |
| | | Neil Sedaka | Songwriter | | 1939 | |
| | | Amy Sedaris | Actor | Strangers With Candy | 1961 | |
| | | Kyra Sedgwick | Actor | The Closer | 1965 | |
| | | Pete Seeger | Musician | | 1919 | |
| | | Ruth Crawford Seeger | Composer | Our Singing Country | 1901 | 1953 |
| | | Jeannie Seely | Musician | | 1940 | |
| | | Erich Segal | Author | Love Story | 1937 | |
| | | Bob Seger | Musician | | 1945 | |
| | | Andres Segovia | Guitarist | Greatest classical guitarist | 1893 | 1987 |
 | | Compay Segundo | Guitarist | Buena Vista Social Club | 1907 | 2003 |
| | | Jerry Seinfeld | Actor | Seinfeld | 1954 | |
| | | Carlos Seixas | Composer | Portuguese composer | 1704 | 1742 |
 | | Mobutu Sese Seko | Head of State | Dictator, bled Zaire dry | 1930 | 1997 |
 | | Haile Selassie | Royalty | Last Emperor of Ethiopia | 1892 | 1975 |
| | | John Selden | Scholar | English orientalist and jurist | 1584 | 1654 |
| | | Tom Selleck | Actor | Magnum, P.I. | 1945 | |
| | | Peter Sellers | Actor | Inspector Clouseau | 1925 | 1980 |
| | | Ben Selvin | Musician | Bandleader | 1898 | 1980 |
| | | Hans Selye | Scientist | First to demonstrate the existence of stress | 1907 | 1983 |
| | | Richard Selzer | Author | Rituals of Surgery | 1928 | |
| | | David O. Selznick | Film/TV Producer | A Star Is Born | 1902 | 1965 |
 | | Hun Sen | Head of State | Prime Minister of Cambodia | 1951 | |
| | | Maurice Sendak | Artist | | 1928 | |
| | | Seneca | Philosopher | Epistulae Morales | 0005 BC | 0065 |
 | | Léopold Senghor | Head of State | President of Senegal, 1960-80 | 1906 | 2001 |
| | | Mack Sennett | Film Director | Founder of Keystone Studios | 1880 | 1960 |
| | | Tullio Serafin | Conductor | Italian opera conductor | 1878 | 1968 |
| | | Rod Serling | Author | Creator of The Twilight Zone | 1924 | 1975 |
| | | Ramon Gomez de la Serna | Playwright | Greguerías | 1888 | 1963 |
| | | Jeff Sessions | Politician | US Senator from Alabama | 1946 | |
| | | Roger Sessions | Composer | Concerto for Orchestra | 1896 | 1985 |
| | | Georges Seurat | Painter | A Sunday on La Grande Jatte | 1859 | 1891 |
| | | Eric Sevareid | Journalist | CBS News journalist | 1912 | 1992 |
| | | Joan Severance | Actor | Dangerous Indiscretion | 1958 | |
| | | Doc Severinsen | Musician | | 1927 | |
| | | Marie de Sevigne | Author | | 1626 | 1696 |
| | | William Seward | Government | Seward's Folly (Alaska) | 1801 | 1872 |
| | | Anna Sewell | Author | Black Beauty | 1820 | 1878 |
| | | Anne Sexton | Poet | Live or Die | 1928 | 1974 |
| | | Jane Seymour | Actor | | 1951 | |
| | | Thomas Shadwell | Playwright | | 1642 | 1692 |
| | | James Shaffer | Guitarist | Korn. | 1970 | |
| | | Peter Shaffer | Playwright | | 1926 | |
 | | Muhammed Zahir Shah | Royalty | King of Afghanistan, 1933-73 | 1914 | 2007 |
 | | Gil Shaham | Violinist | | 1971 | |
| | | William Shakespeare | Playwright | Romeo and Juliet, Hamlet, Macbeth | 1564 | 1616 |
 | | Shakira | Musician | Most popular performer from Latin America? | 1977 | |
| | | Tupac Shakur | Rapper | Rapper shot in Las Vegas drive-by | 1971 | 1996 |
| | | Tom Shales | Critic | TV critic | 1944 | |
| | | Tony Shalhoub | Actor | Monk, Men In Black, etc. | 1953 | |
| | | Garry Shandling | Comic | Larry Sanders | 1949 | |
 | | Yang Shangkun | Head of State | President of the PRC, 1988-93 | 1907 | 1998 |
| | | Ravi Shankar | Musician | | 1920 | |
| | | Bill Shankly | Soccer | Won seven Scottish caps | 1914 | 1981 |
| | | Del Shannon | Musician | 1960s songwriter, Runaway | 1934 | 1990 |
| | | Molly Shannon | Comic | Saturday Night Live | 1964 | |
| | | Robert Shapiro | Attorney | One of OJ Simpson's attorneys | 1942 | |
| | | Samuel H. Shapiro | Politician | Governor of Illinois, 1968-69 | 1907 | 1987 |
| | | Ted Shapiro | Composer | If I Had You | 1899 | 1980 |
| | | Omar Sharif | Actor | Lawrence of Arabia | 1932 | |
| | | Tom Sharpe | Author | | 1928 | |
| | | Al Sharpton | Activist | Pentecostal minister | 1954 | |
| | | Sonny Sharrock | Guitarist | Free jazz guitarist | 1940 | 1994 |
| | | William Shatner | Actor | | 1931 | |
| | | Artie Shaw | Jazz Musician | | 1910 | 2004 |
| | | George Bernard Shaw | Playwright | Irish dramatist & socialist | 1856 | 1950 |
| | | Irwin Shaw | Playwright | Rich Man, Poor Man | 1913 | 1984 |
| | | Lindsey Shaw | Actor | Moze on Ned's Declassified | 1989 | |
| | | Reta Shaw | Actor | The Ghost and Mrs. Muir | 1912 | 1982 |
| | | Alia Shawkat | Actor | Maeby on Arrested Development | 1989 | |
| | | Ted Shawn | Dancer | Jacob's Pillow Dance Festival | 1891 | 1972 |
| | | Wallace Shawn | Actor | My Dinner with Andre | 1943 | |
| | | William Shawn | Journalist | Editor of The New Yorker | 1907 | 1992 |
| | | R.E. Shay | | | 0000 | |
| | | Rodion Shchedrin | Composer | | 1932 | |
| | | George Beverly Shea | Singer/Songwriter | How Great Thou Art | 1909 | |
| | | Harry Shearer | Actor | Almost half the voices on The Simpsons | 1943 | |
| | | Norma Shearer | Actor | The Divorcee | 1902 | 1983 |
| | | George Shearing | Jazz Musician | British jazz pianist | 1919 | |
| | | Gail Sheehy | Author | 1999 biography of Hillary Clinton, Hillary's Choic | 1937 | |
| | | Charlie Sheen | Actor | Spin City | 1956 | |
| | | Fulton J. Sheen | Religion | Television's first preacher | 1895 | 1979 |
| | | Martin Sheen | Actor | The West Wing | 1940 | |
| | | Sheila E | Musician | Child prodigy Latin percussionist | 1957 | |
| | | Richard Shelby | Politician | US Senator from Alabama | 0000 | |
| | | Mary Shelley | Author | Frankenstein | 1797 | 1851 |
| | | Percy Bysshe Shelley | Poet | Prometheus Unbound | 1792 | 1822 |
| | | Adrienne Shelly | Actor | Waitress | 1966 | 2006 |
| | | Bright Sheng | Composer | The Silver River | 1955 | |
| | | William Shenstone | Poet | The Schoolmistress | 1714 | 1763 |
| | | Jean Shepard | Country Musician | The Grand Lady of the Grand Ole Opry | 1933 | |
| | | Sam Shepard | Playwright | Pulitzer for Buried Child | 1943 | |
| | | Cybill Shepherd | Actor | | 1950 | |
| | | Sherri Shepherd | Actor | Ramona Platt on Less Than Perfect | 1967 | |
| | | Ann Sheridan | Actor | | 1915 | 1967 |
| | | General Philip Sheridan | Military | Union Army General | 1831 | 1888 |
| | | Allan Sherman | Musician | Hello Muddah, Hello Fadduh | 1924 | 1973 |
| | | Bobby Sherman | Actor | | 1943 | |
| | | Cindy Sherman | Photographer | The Untitled Film Stills | 1954 | |
| | | Richard M. Sherman | Songwriter | | 1928 | |
| | | Robert B. Sherman | Songwriter | Mary Poppins | 1925 | |
| | | William T. Sherman | Military | Marched to the Sea | 1820 | 1891 |
| | | Charles Sherrington | Doctor | Neurons and synapses | 1857 | 1952 |
| | | Robert E. Sherwood | Playwright | Robert Emmet Sherwood | 1896 | 1915 |
| | | Brooke Shields | Actor | Suddenly Susan | 1965 | |
| | | Harry Shields | Musician | | 1899 | 1971 |
| | | Larry Shields | Jazz Musician | American dixieland jazz clarinetist. | 1893 | 1953 |
| | | Nat Shilkret | Composer | Concerto for Trombone | 1895 | 1982 |
| | | Armin Shimerman | Actor | Quark on Star Trek: Deep Space Nine | 1949 | |
 | | Thaksin Shinawatra | Head of State | Prime Minister of Thailand, 2001-06 | 1949 | |
| | | John Shirley-Quirk | Singer | English bass-baritone | 1931 | |
| | | Allan Shivers | Politician | Governor of Texas, 1949-57 | 1907 | 1985 |
| | | Shock G | Rapper | Digital Underground | 1963 | |
| | | Michelle Shocked | Singer/Songwriter | Short Sharp Shocked | 1962 | |
| | | William Shockley | Physicist | Co-Inventor of the transistor | 1910 | 1989 |
| | | Willie Shoemaker | Jockey | Greatest 20th century jockey | 1931 | 2003 |
| | | Stephen H. Sholes | Business | Prominent recording executive with RCA Victor | 1911 | 1968 |
| | | Dinah Shore | Singer | | 1916 | 1994 |
| | | Pauly Shore | Comic | Encino Man | 1968 | |
| | | Bobby Short | Singer | Cabaret singer at the Carlyle Hotel | 1924 | 2005 |
| | | Clare Short | Politician | | 1946 | |
| | | Martin Short | Actor | | 1950 | |
| | | Wayne Shorter | Jazz Musician | Influential sax player and jazz composer | 1933 | |
| | | Dmitri Shostakovich | Composer | Symphony No. 5 | 1906 | 1975 |
| | | David M. Shoup | Military | 22nd Commandant of the Marine Corps | 1904 | 1983 |
| | | Eric Show | Baseball | | 1956 | 1994 |
| | | Jean Shrimpton | Model | Top 1960's supermodel | 1942 | |
| | | Maria Shriver | Journalist | Married to Arnold Schwarzenegger | 1955 | |
| | | Sargent Shriver | Politician | Ran for VP with George McGovern | 1915 | |
| | | Sonny Shroyer | Actor | Enos on The Dukes of Hazzard | 1935 | |
| | | Elisabeth Shue | Actor | Leaving Las Vegas | 1963 | |
| | | Don Shula | Football | Miami Dolphins coach | 1930 | |
| | | Mort Shuman | Singer/Songwriter | Viva Las Vegas | 1936 | 1991 |
| | | Oscar Shumsky | Violinist | American violinist and conductor | 1917 | 2000 |
| | | Jean Sibelius | Composer | Finlandia | 1865 | 1957 |
| | | Walter Sickert | Painter | | 1860 | 1942 |
| | | Sarah Siddons | Actor | 18th century English tragic actress | 1755 | 1831 |
| | | Hugh Sidey | Journalist | Time magazine | 1927 | 2005 |
| | | Philip Sidney | Author | The Defence of Poesie | 1554 | 1586 |
| | | Don Siegel | Film Director | Dirty Harry | 1912 | 1991 |
| | | Joel Siegel | Critic | Film critic | 1943 | 2007 |
| | | Elie Siegmeister | Composer | American composer, educator and author | 1909 | 1991 |
| | | Sigismund | Royalty | Holy Roman Emperor, 1433-37 | 1368 | 1437 |
| | | Carl Sigman | Songwriter | Ebb Tide | 1909 | 2000 |
| | | Simone Signoret | Actor | Ship of Fools | 1921 | 1985 |
| | | Norodom Sihanouk | Royalty | King of Cambodia | 1922 | |
| | | Igor Sikorsky | Aviator | Designed the first successful helicopter | 1889 | 1972 |
| | | Beverly Sills | Singer | Coloratura soprano | 1929 | 2007 |
| | | Henry Silva | Actor | The Manchurian Candidate | 1928 | |
| | | Horace Silver | Jazz Musician | Song For My Father | 1928 | |
| | | Fred Silverman | Film/TV Producer | TV producer and executive | 1937 | |
| | | Jonathan Silverman | Actor | The Single Guy | 1966 | |
| | | Sarah Silverman | Actor | Mr. Show, The Larry Sanders Show | 1970 | |
| | | Phil Silvers | Actor | You're in the Army Now | 1911 | 1985 |
| | | Shel Silverstein | Author | Where the Sidewalk Ends, A Boy Named Sue | 1930 | 1999 |
| | | Alicia Silverstone | Actor | Clueless | 1976 | |
| | | Alastair Sim | Actor | Scrooge in A Christmas Carol | 1900 | 1976 |
| |  | Charles Simic | Poet | The World Doesn't End | 1938 | |
| | | Gene Simmons | Bassist | KISS bassist | 1949 | |
| | | Nick Simmons | Relative | Son of Gene Simmons | 1989 | |
| | | William Gilmore Simms | Historian | | 1806 | 1870 |
| | | Carly Simon | Musician | | 1945 | |
| | | John Simon | Author | | 1925 | |
| | | Neil Simon | Playwright | The Odd Couple | 1927 | |
| | | Norton Simon | Business | Founder of the Norton Simon Museum | 1907 | 1993 |
| | | Paul Simon | Singer/Songwriter | Simon and Garfunkel | 1941 | |
| | | John A. Simone Sr. | | | 0000 | |
| | | Nina Simone | Singer | The High Priestess of Soul | 1933 | 2003 |
| | | Alan Simpson | Politician | US Senator from Wyoming, 1979-97 | 1931 | |
| | | Ashlee Simpson | Singer | Jessica Simpson's younger sister | 1984 | |
| | | George Gaylord Simpson | Paleontologist | Expert on extinct mammals | 1902 | 1984 |
| | | Jessica Simpson | Singer | MTV Newlyweds | 1980 | |
| | | Louis Simpson | Poet | At The End of the Open Road | 1923 | |
| | | O. J. Simpson | Actor | | 1947 | |
| | | Valerie Simpson | Musician | Half of Ashford and Simpson | 1946 | |
| | | Molly Sims | Actor | Delinda Deline on Las Vegas | 1973 | |
| | | Zoot Sims | Jazz Musician | Tenor and soprano saxophonist | 1925 | 1985 |
| | | Jaime Cardinal Sin | Religion | Archbishop of Manila | 1928 | 2005 |
| | | Frank Sinatra | Singer | One of the finest vocalists of all time | 1915 | 1998 |
| | | Nancy Sinatra | Actor | | 1940 | |
| | | Sinbad | Actor | A Different World | 1956 | |
| | | Upton Sinclair | Novelist | The Jungle | 1878 | 1968 |
| | | Donald Sinden | Actor | | 1923 | |
 | | Christian Sinding | Composer | Norwegian composer | 1856 | 1941 |
| | | Isaac Bashevis Singer | Author | Yentl, the Yeshiva Boy | 1904 | 1991 |
 | | Vijay Singh | Golf | Winner of 2004 PGA Championship | 1963 | |
| | | Penny Singleton | Actor | Blondie | 1908 | 2003 |
 | | Fouad Siniora | Head of State | Prime Minister of Lebanon | 1943 | |
| | | Giuseppe Sinopoli | Conductor | Conductor and composer | 1946 | 2001 |
| | | Marina Sirtis | Actor | Deana Troi on ST:TNG | 1955 | |
| | | Gene Siskel | Critic | Siskel and Ebert | 1946 | 1999 |
| | | Noble Sissle | Jazz Musician | | 1889 | 1975 |
| | | Edith Sitwell | Poet | Façade | 1887 | 1964 |
| | | Osbert Sitwell | Author | Belshazzar's Feast libretto | 1892 | 1969 |
| | | Nikki Sixx | Bassist | Mötley Crüe bassist | 1958 | |
| | | John R. Sizoo | Government | | 0000 | |
| | | Ricky Skaggs | Country Musician | Country music singer | 1954 | |
 | | Nikolaos Skalkottas | Composer | Composer, Second Viennese School | 1904 | 1949 |
| | | Red Skelton | Actor | The Red Skelton Show | 1913 | 1997 |
| | | Tom Skerritt | Actor | Viper in Top Gun | 1933 | |
| | | B. F. Skinner | Psychologist | Radical Behaviorism | 1904 | 1990 |
| | | Cornelia Otis Skinner | Actor | | 1901 | 1979 |
| | | Frank Skinner | Comic | Three Lions | 1957 | |
| | | Slash | Guitarist | Former lead guitarist, Guns n' Roses | 1965 | |
| | | Christian Slater | Actor | Kuffs, True Romance | 1969 | |
| | | Leonard Slatkin | Conductor | American conductor | 1944 | |
| | | Enos Slaughter | Baseball | Right Fielder | 1916 | 2002 |
| | | Percy Sledge | Singer | When a Man Loves a Woman | 1941 | |
| | | Erika Slezak | Actor | One Life to Live | 1946 | |
| | | Grace Slick | Singer | Jefferson Airplane and Starship | 1939 | |
| | | Slim Thug | Rapper | Already Platinum | 1980 | |
| | | Curtis Sliwa | Activist | Founder of the Guardian Angels | 1954 | |
| | | Alfred P. Sloan | Business | | 1875 | 1966 |
| | | John Sloan | Artist | Sixth Avenue Elevated at Third Street | 1871 | 1951 |
| | | Nicolas Slonimsky | Author | | 1894 | 1995 |
| | | Amy Smart | Actor | Outside Providence | 1976 | |
| | | Christopher Smart | Poet | A Song to David | 1722 | 1771 |
| | | Jean Smart | Actor | Charlene on Designing Women | 1959 | |
| | | Lewis B. Smedes | Author | | 1921 | 2002 |
| | | Bedrich Smetana | Composer | My Country | 1824 | 1884 |
| | | Jane Smiley | Novelist | A Thousand Acres | 1949 | |
| |  | Yakov Smirnoff | Comic | What a country! | 1951 | |
| | | Adam Smith | Economist | Wealth of Nations | 1723 | 1790 |
| | | Al Smith | Government | Twice Governor of New York | 1873 | 1944 |
| | | Alexis Smith | Actor | Here Comes the Groom | 1921 | 1993 |
| | | Anna Nicole Smith | Model | The Anna Nicole Show | 1967 | 2007 |
| | | Bessie Smith | Singer | Empress of the Blues | 1894 | 1937 |
| | | Betty Smith | Novelist | A Tree Grows in Brooklyn | 1896 | 1972 |
| | | Carl Smith | Musician | | 1927 | |
| | | Connie Smith | Country Musician | Once a Day | 1941 | |
| | | Daniel Wayne Smith | Relative | Anna Nicole Smith's son | 1986 | 2006 |
| | | David Smith | Sculptor | Abstract Expressionist sculptor | 1906 | 1965 |
| | | Dodie Smith | Novelist | The Hundred and One Dalmatians | 1896 | 1990 |
| | | F. E. Smith | Attorney | Winston Churchill's greatest personal and politica | 1872 | 1930 |
| | | H. Allen Smith | Author | Low Man on a Totem Pole | 1907 | 1976 |
| | | Hal Smith | Actor | Otis Campbell on The Andy Griffith Show | 1916 | 1994 |
| | | Harry B. Smith | Songwriter | The Serenade | 1860 | 1936 |
| | | Iain Duncan Smith | Politician | Conservative Party leader, 2001-03 | 1954 | |
| | | Jaclyn Smith | Actor | Former Charlie's Angel | 1945 | |
| | | Jimmy Smith | Jazz Musician | Hammond B-3 organist | 1925 | 2005 |
| | | Joseph Smith | Religion | Founded the Mormon faith | 1805 | 1844 |
| | | Kate Smith | Singer | God Bless America | 1907 | 1986 |
| | | Keely Smith | Musician | | 1932 | |
| | | Kent Smith | Actor | Cat People | 1907 | 1985 |
| | | Liz Smith | Columnist | American gossip columnist. | 1923 | |
| | | Logan Pearsall Smith | Essayist | Unforgotten Years | 1865 | 1946 |
| | | Maggie Smith | Actor | Prof. McGonagall in Harry Potter | 1934 | |
| | | Margaret Chase Smith | Politician | US Senator from Maine, 1949-73 | 1897 | 1995 |
| | | Martin Smith | Musician | Delirious? | 1970 | |
| | | Patti Smith | Singer | Horses | 1946 | |
| | | Roy L. Smith | Religion | | 0000 | |
| | | Samantha Smith | Activist | America's Youngest Ambassador | 1972 | 1985 |
| | | Samuel Francis Smith | Composer | My Country, 'Tis of Thee | 1808 | 1895 |
| | | Stevie Smith | Poet | Not Waving but Drowning | 1902 | 1971 |
| | | Sydney Smith | Religion | Instigated the Edinburgh Review | 1771 | 1845 |
| | | Tracy Smith | TV Personality | | 0000 | |
| | | Trey Smith | Actor | Son of Will Smith | 1992 | |
| | | Will Smith | Actor | Fresh Prince of Bel Air | 1968 | |
| | | Willie "The Lion" Smith | Jazz Musician | American jazz pianist | 1897 | 1973 |
| | | Jurnee Smollett | Actor | On Our Own | 1986 | |
| | | Tobias Smollett | Novelist | The Adventures of Roderick Random | 1721 | 1771 |
| | | Sam Snead | Golf | | 1912 | 2002 |
| | | Carrie Snodgress | Actor | Diary of a Mad Housewife | 1946 | 2004 |
| | | Brittany Snow | Actor | Meg Pryor on American Dreams | 1986 | |
| | | C. P. Snow | Author | The Two Cultures and the Scientific Revolution | 1905 | 1980 |
| | | Carrie Snow | Comic | 7,000 Sailors Can’t Be Wrong | 0000 | |
| | | Hank Snow | Country Musician | I'm Movin' On | 1914 | 1999 |
| | | Mark Snow | Composer | Prolific composer for film and television | 1946 | |
| | | Elmer Snowden | Jazz Musician | Banjo player | 1900 | 1973 |
| | | Jimmy The Greek Snyder | TV Personality | Oddsmaker | 1918 | 1996 |
| | | Ted Snyder | Songwriter | The Sheik of Araby | 1881 | 1965 |
| | | Tom Snyder | Talk Show Host | The Tomorrow Show | 1936 | |
| | | Socrates | Philosopher | Socratic Method | 0470 BC | 0399 BC |
| | | Steven Soderbergh | Film Director | Traffic | 1963 | |
| | | Camila Sodi | Actor | Niece of Thalía | 1986 | |
| | | Solage | Composer | Chantilly Codex | 1360 | 1403 |
 | | Juan María Solare | Composer | Argentine composer and pianist | 1966 | |
| | | Antonio Soler | Composer | Keyboard sonatas | 1729 | 1783 |
| | | Robert Solow | Economist | Theory of economic growth | 1924 | |
| | | Georg Solti | Conductor | Chicago Symphony Orchestra 1969-1991 | 1912 | 1997 |
| | | Aleksandr Solzhenitsyn | Author | One Day in the Life of Ivan Denisovich | 1918 | 2008 |
| | | Brett Somers | Actor | Match Game fixture | 1927 | 2007 |
| | | Suzanne Somers | Actor | Chrissy on Three's Company | 1946 | |
| | | Elke Sommer | Actor | Deadlier Than the Male | 1940 | |
| | | Gale Sondergaard | Actor | Anthony Adverse | 1899 | 1985 |
| | | Stephen Sondheim | Composer | Composer of musicals | 1930 | |
| | | Brenda Song | Actor | London Tipton on Zack and Cody | 1988 | |
| | | Susan Sontag | Author | Novelist, critic, intellectual | 1933 | 2004 |
| | | Jack Soo | Actor | Det. Yemana on Barney Miller | 1916 | 1979 |
| | | Sophocles | Playwright | Oedipus the King | 0496 BC | 0406 BC |
| | | Fernando Sor | Composer | | 1778 | 1839 |
| | | Kaikhosru Shapurji Sorabji | Composer | Opus Clavicembalisticum | 1892 | 1988 |
 | | Alfonso Soriano | Baseball | Chicago Cubs | 0000 | |
| | | George Soros | Business | Hungarian financial speculator | 1930 | |
| | | Mira Sorvino | Actor | Mighty Aphrodite | 1967 | |
| | | Sammy Sosa | Baseball | Over 600 Home Runs | 1968 | |
| | | Shannyn Sossamon | Actor | A Knight's Tale | 1978 | |
| | | David Soul | Actor | Hutch on Starsky and Hutch | 1946 | |
| | | John Philip Sousa | Musician | Stars and Stripes Forever | 1854 | 1932 |
| | | David Souter | Judge | US Supreme Court Justice | 1939 | |
| | | Robert Southey | Poet | A Vision of Judgment | 1774 | 1843 |
| | | Robert Southwell | Saint | New Heaven, New War | 1561 | 1595 |
| | | Gérard Souzay | Singer | French baritone singer | 1918 | 2004 |
| | | Leo Sowerby | Composer | | 1895 | 1968 |
 | | Wole Soyinka | Playwright | 1986 Nobel prize for literature | 1934 | |
| | | Sissy Spacek | Actor | Coal Miner's Daughter | 1949 | |
| | | Kevin Spacey | Actor | | 1959 | |
| | | David Spade | Actor | The Showbiz Show | 1964 | |
| | | James Spader | Actor | Sex, Lies, and Videotape | 1960 | |
| | | Muriel Spark | Novelist | The Prime of Miss Jean Brodie | 1918 | 2006 |
| | | Jordin Sparks | Singer | Winner, 6th season American Idol | 1989 | |
| | | Larry Speakes | Government | White House Press Secretary for Ronald Reagan | 1939 | |
| | | Britney Spears | Singer | Oops!... I Did it Again | 1981 | |
| | | Phil Spector | Music Producer | "Wall of Sound "Creator | 1940 | |
| | | Ronnie Spector | Singer | The Ronettes | 1942 | |
| | | Albert Speer | Architect | Hitler's architect | 1905 | 1981 |
| | | Candy Spelling | Activist | Widow of Aaron Spelling. | 0000 | |
| | | Tori Spelling | Actor | | 1973 | |
 | | Baldwin Spencer | Head of State | 3rd Prime Minister of Antigua and Barbuda | 1948 | |
| | | Herbert Spencer | Philosopher | Synthetic Philosophy | 1820 | 1903 |
| | | Len Spencer | Musician | | 1867 | 1914 |
| | | Stanley Spencer | Painter | | 1891 | 1959 |
| | | Tracie Spencer | Singer | This House | 1976 | |
| | | Oswald Spengler | Philosopher | | 1880 | 1936 |
| | | Edmund Spenser | Poet | The Faerie Queene | 1552 | 1599 |
| | | Wendie Jo Sperber | Actor | Amy on Bosom Buddies | 1958 | 2005 |
| | | Steven Spielberg | Film Director | E.T., 1941 | 1946 | |
| | | Mickey Spillane | Author | Mike Hammer novels | 1918 | 2006 |
 | | Benedict Spinoza | Philosopher | On the Improvement of the Understanding | 1632 | 1677 |
| | | Benjamin Spock | Author | Baby and Child Care | 1903 | 1998 |
| | | Ludwig Spohr | Composer | Four clarinet concertos | 1784 | 1859 |
| | | Gaspare Spontini | Composer | La vestale | 1774 | 1851 |
| | | William Archibald Spooner | Scholar | Spoonerism inventor | 1844 | 1930 |
| | | Alicia Ann Spottiswoode | Songwriter | Annie Laurie | 1810 | 1900 |
| | | Dusty Springfield | Singer | Son of a Preacher Man | 1939 | 1999 |
| | | Rick Springfield | Musician | Jessie's Girl | 1949 | |
| | | Bruce Springsteen | Musician | The Boss | 1949 | |
| | | Charles Spurgeon | Religion | British Reformed Baptist preacher | 1834 | 1892 |
| | | Johanna Spyri | Author | Heidi. | 1827 | 1901 |
| | | Antonio Squarcialupi | Composer | | 1416 | 1480 |
| | | Lili St. Cyr | Actor | | 1918 | 1999 |
 | | St. Jerome | Saint | Church Father, translated Vulgate | 0340 | 0420 |
| | | Oliver St. John Gogarty | Doctor | | 1878 | 1957 |
| | | Jill St. John | Actor | Tiffany Case in Diamonds Are Forever | 1940 | |
| | | Adela Rogers St. Johns | Journalist | "Girl reporter" during the 1920s and 1930s | 1894 | 1988 |
| | | Jean Stafford | Novelist | | 1915 | 1979 |
| | | Jo Stafford | Singer | American pop singer | 1917 | 2008 |
| | | Thomas P. Stafford | Astronaut | Gemini 6 & 9, Apollo 10, Apollo-Soyuz | 1930 | |
| | | Amos Alonzo Stagg | Football | American collegiate coach | 1862 | 1965 |
| | | Harley O. Staggers Sr. | Politician | Congressman from West Virginia, 1949-81 | 1907 | 1991 |
| | | Nick Stahl | Actor | Carnivŕle | 1979 | |
| | | Jewel Staite | Actor | Kaylee Frye on Firefly | 1982 | |
| | | Layne Staley | Musician | Frontman for Alice In Chains | 1967 | 2002 |
| |  | Josef Stalin | Head of State | Dictator, Soviet Union | 1879 | 1953 |
| | | Carl Stalling | Composer | Composer for hundreds of Looney Tunes | 1891 | 1972 |
| | | Sylvester Stallone | Actor | | 1946 | |
| | | Anton Stamitz | Composer | Composer and violinist | 1750 | 1809 |
| | | Carl Philipp Stamitz | Composer | | 1745 | 1801 |
| | | Johann Stamitz | Composer | | 1717 | 1757 |
| | | John Stamos | Actor | Jesse on Full House | 1963 | |
| | | Charles Villiers Stanford | Composer | Irish composer | 1852 | 1924 |
| | | Ivan Stang | Religion | Church of the SubGenius | 1954 | |
| | | Konstantin Stanislavski | Actor | Russian actor and theatre director. | 1863 | 1938 |
| | | Stanislaw Skrowaczewski | Conductor | Minnesota Orchestra 1960-1980 | 1923 | |
| | | Augustus O. Stanley | Politician | US Senator from Kentucky, 1919-25 | 1867 | 1958 |
| | | Frank Stanley | Singer | | 0000 | 1910 |
| | | Ralph Stanley | Country Musician | Bluegrass musician | 1927 | |
| | | Elizabeth Cady Stanton | Activist | National Woman Suffrage Association | 1815 | 1902 |
| | | Barbara Stanwyck | Actor | Double Indemnity | 1907 | 1990 |
| | | Maureen Stapleton | Actor | | 1925 | 2006 |
| | | Chez Starbuck | Actor | The Thirteenth Year | 1982 | |
| | | János Starker | Cellist | | 1924 | |
| | | Kay Starr | Singer | The Rock And Roll Waltz | 1922 | |
| | | Ringo Starr | Musician | Beatle | 1940 | |
| | | Harold Stassen | Politician | Perennial presidential candidate | 1907 | 2001 |
| | | Claus von Stauffenberg | Military | Tried to kill Hitler in 1944 | 1907 | 1944 |
| | | Christina Stead | Novelist | | 1902 | 1983 |
| | | Edmund Clarence Stedman | Poet | The Blameless Prince | 1833 | 1908 |
| | | Danielle Steel | Novelist | Romance novelist | 1947 | |
| | | Bob Steele | Actor | Trooper Duffy on F Troop | 1907 | 1988 |
| | | Cassie Steele | Actor | Degrassi: The Next Generation | 1989 | |
| | | Michael Steele | Bassist | | 1955 | |
| | | Michael Steele | Politician | Lt. Governor of Maryland, 2003-07 | 1958 | |
| | | Gwen Stefani | Singer | No Doubt | 1969 | |
| | | Vilhjalmur Stefansson | Explorer | Canadian Arctic explorer and ethnologist | 1879 | 1962 |
| | | Agostino Steffani | Composer | Italian ecclesiastic, diplomat and composer | 1653 | 1728 |
 | | Karrine Steffans | Model | Confessions of a Video Vixen | 1978 | |
| | | Wallace Stegner | Author | The Angle of Repose | 1909 | 1993 |
| | | Edward Steichen | Photographer | | 1879 | 1973 |
| | | William Steig | Cartoonist | Shrek, The New Yorker | 1907 | 2003 |
| | | Rod Steiger | Actor | | 1925 | 2002 |
| | | Ben Stein | Game Show Host | Host of Win Ben Stein's Money | 1944 | |
| | | Gertrude Stein | Author | Avant-garde writer, salon | 1874 | 1946 |
| | | Horst Stein | Conductor | Bamberg Symphony Orchestra | 1928 | 2008 |
| | | John Steinbeck | Novelist | The Grapes of Wrath | 1902 | 1968 |
| | | David Steinberg | Comic | Second City alumnus | 1942 | |
| |  | Saul Steinberg | Cartoonist | The New Yorker magazine | 1914 | 1999 |
| | | George Steinbrenner | Baseball | Owner, New York Yankees | 1930 | |
| | | Gloria Steinem | Activist | Founder, Ms. Magazine | 1934 | |
| | | George Steiner | Critic | After Babel | 1929 | |
| | | Max Steiner | Film/TV Music Composer | Gone with the Wind | 1888 | 1971 |
| | | Charles Steinmetz | Scientist | | 1865 | 1923 |
| | | Stendhal | Author | Le Rouge et le Noir | 1783 | 1842 |
| | | Casey Stengel | Baseball | The Old Perfesser | 1890 | 1975 |
 | | Wilhelm Stenhammar | Composer | | 1871 | 1927 |
| | | George Stephanopoulos | TV Personality | | 1961 | |
| | | Stephen Jay Gould | Biologist | Evolutionary biologist and paleontologist | 1941 | 2002 |
| | | Neal Stephenson | Novelist | Snow Crash | 1959 | |
| | | Stephen_Spender | Poet | | 1909 | 1995 |
| | | Andrew B. Sterling | Songwriter | Wait 'till the Sun Shines, Nellie | 1874 | 1955 |
| | | Jan Sterling | Actor | | 1921 | 2004 |
| | | Robert Sterling | Actor | George Kerby on Topper | 1917 | 2006 |
| | | Avraham Stern | Military | Founder of Lohamei Herut Israel | 1907 | 1942 |
| | | Daniel Stern | Actor | City Slickers | 1957 | |
| | | Howard Stern | Radio Personality | The Howard Stern Show | 1954 | |
| | | Isaac Stern | Violinist | Violin virtuoso | 1920 | 2001 |
| | | Joseph W. Stern | Business | | 1870 | 1934 |
| | | Zalman Stern | Computer Programmer | Former ITC hacker | 0000 | |
| | | Laurence Sterne | Novelist | Tristram Shandy | 1713 | 1768 |
| | | Albert Sterner | Artist | | 1863 | 1946 |
| | | Cat Stevens | Singer/Songwriter | | 1948 | |
| | | Connie Stevens | Singer | Hawaiian Eye | 1938 | |
| | | John Stevens | Drummer | | 1940 | 1994 |
| | | Rachel Stevens | Musician | In UK pop band S Club 7 | 1978 | |
| | | Shadoe Stevens | Game Show Host | The voice of Hollywood Squares | 1947 | |
| | | Ted Stevens | Politician | US Senator from Alaska | 1923 | |
| | | Wallace Stevens | Poet | Harmonium | 1879 | 1955 |
| | | Adlai Stevenson | Politician | Governor of Illinois, 1949-53 | 1900 | 1965 |
| | | Elise Stevenson | Singer | | 0000 | |
| | | Robert Louis Stevenson | Author | Treasure Island | 1850 | 1894 |
| | | Al Stewart | Singer/Songwriter | Year of the Cat | 1945 | |
| | | Cal Stewart | Comic | Recording pioneer | 1856 | 1919 |
| | | Dave Stewart | Musician | Male half of the Eurythmics | 1952 | |
| | | James Stewart | Actor | Mr. Smith Goes to Washington | 1908 | 1997 |
| | | Jon Stewart | Comic | Anchor of The Daily Show | 1962 | |
| | | Martha Stewart | Business | Professional housekeeper | 1941 | |
| | | Mary Stewart | Novelist | Merlin | 1916 | |
| | | Patrick Stewart | Actor | Captain Picard in Star Trek: TNG | 1940 | |
| | | Potter Stewart | Judge | US Supreme Court Justice | 1915 | 1985 |
| | | Rod Stewart | Musician | Da Ya Think I'm Sexy? | 1945 | |
| | | David Ogden Stiers | Actor | Maj. Winchester on M*A*S*H | 1942 | |
| | | Julia Stiles | Actor | 10 Things I Hate About You | 1981 | |
| | | William Grant Still | Composer | Symphony No. 1 "Afro-American" | 1895 | 1978 |
| | | Ben Stiller | Actor | There's Something About Mary | 1965 | |
| | | Al Stillman | Songwriter | | 1906 | 1979 |
| | | Stephen Stills | Musician | Crosby, Stills, and Nash | 1945 | |
| | | Joseph Stilwell | Military | Led US and Chinese forces in WWII China | 1883 | 1946 |
| | | Henry L. Stimson | Government | US Secretary of War 1911-13, 1940-45 | 1867 | 1950 |
| | | Sting | Singer/Songwriter | Lead singer of The Police | 1951 | |
| | | Darryl Stingley | Football | Wide reciever - New England Patriots | 1951 | 2004 |
| | | Max Stirner | Philosopher | Existential German nihilo-anarchist | 1806 | 1856 |
| | | Frederick Stock | Conductor | Chicago Symphony | 1872 | 1942 |
| | | James Stockdale | Military | H. Ross Perot's would-be Vice President | 1923 | 2005 |
| | | Karlheinz Stockhausen | Composer | Influential avant-garde composer | 1928 | |
| | | Carl B. Stokes | Politician | | 1927 | 1996 |
| | | Leopold Stokowski | Conductor | Fantasia, Philadelphia Orchestra | 1882 | 1977 |
| | | Clifford Stoll | Author | | 0000 | |
| | | Mike Stoller | Songwriter | | 1933 | |
| | | Eric Stoltz | Actor | Chicago Hope | 1961 | |
| | | Robert Stoltz | Songwriter | Austrian songwriter and conductor | 1880 | 1975 |
| | | Gottfried Heinrich Stölzel | Composer | German composer | 1690 | 1749 |
| | | I. F. Stone | Journalist | I. F. Stone's Weekly | 1907 | 1989 |
| | | Irving Stone | Novelist | Historical biographical novelist | 1903 | 1989 |
| | | Melville E. Stone | Publisher | Founder of the Chicago Daily News | 1848 | 1929 |
| | | Oliver Stone | Film Director | JFK | 1946 | |
| | | Sharon Stone | Actor | Basic Instinct | 1958 | |
| | | Sly Stone | Singer | | 1944 | |
| | | W. Clement Stone | Business | Success System That Never Fails | 1902 | 2002 |
| | | Tom Stoppard | Playwright | Rosencrantz and Guildenstern are Dead | 1937 | |
| | | Tempest Storm | Actor | American burlesque star | 1928 | |
| | | Kirsten Storms | Actor | General Hospital | 1984 | |
| | | Alan Stout | Composer | American composer of contemporary classical music | 1932 | |
| | | Rex Stout | Novelist | Nero Wolf novels | 1886 | 1975 |
| | | Harriet Beecher Stowe | Author | | 1811 | 1896 |
| | | Madeleine Stowe | Actor | The Last of the Mohicans | 1958 | |
| | | Walafrid Strabo | Religion | Glosa ordinaria | 0808 | 0849 |
| | | Gordon Strachan | Soccer | | 1957 | |
| | | Lytton Strachey | Author | Eminent Victorians | 1880 | 1932 |
| | | J Michael Straczynski | Film/TV Producer | Babylon 5 | 1954 | |
| | | Alessandro Stradella | Composer | S. Giovanni Battista | 1639 | 1682 |
| | | Michael Strahan | Football | NY Giants Defensive End | 1971 | |
| | | George Strait | Country Musician | | 1952 | |
| | | Steven Strait | Model | The Covenant | 1986 | |
| | | Hank Stram | Football | Hall-of-fame NFL coach, KC Chiefs | 1923 | 2005 |
| | | Paul Strand | Photographer | Wall Street | 1890 | 1973 |
| | | John de Stratford | Religion | Archbishop of Canterbury, 1333-48 | 0000 | 1348 |
| | | Dorothy Stratten | Actor | Actress, centerfold | 1960 | 1980 |
| | | Trish Stratus | Wrestling | 100% Stratusfaction Guaranteed | 1975 | |
| | | Johann Strauss I | Composer | Täuberl-Walzer | 1804 | 1849 |
| | | Johann Strauss II | Composer | The Blue Danube | 1825 | 1899 |
| | | Eduard Strauss | Composer | | 1835 | 1916 |
| | | Josef Strauss | Composer | Brother of Johann Strauss II | 1827 | 1870 |
| | | Richard Strauss | Composer | Also sprach Zarathustra | 1864 | 1949 |
| | | Igor Stravinsky | Composer | The Rite of Spring | 1882 | 1971 |
| | | Billy Strayhorn | Composer | Take the A Train | 1915 | 1967 |
| | | Meryl Streep | Actor | | 1949 | |
| | | Barbra Streisand | Actor | | 1942 | |
| | | August Strindberg | Playwright | Röda Rummet | 1849 | 1912 |
| | | Ken Stringfellow | Musician | Posies, R.E.M | 1968 | |
 | | Alfredo Stroessner | Head of State | Dictator of Paraguay, 1954-89 | 1912 | 2003 |
| | | Anna Louise Strong | Journalist | Soviet government promoter | 1885 | 1970 |
| | | Barrett Strong | Singer/Songwriter | | 1941 | |
| | | Don Stroud | Actor | Capt. Pat Chambers on Mike Hammer | 1943 | |
| | | Charles Strouse | Composer | | 1928 | |
| | | Barbara Strozzi | Composer | Italian Baroque singer and composer | 1619 | 1677 |
| | | Joe Strummer | Musician | Lead singer of The Clash | 1952 | 2002 |
| | | Jud Strunk | Singer/Songwriter | Daisy a Day | 1936 | 1981 |
| | | William Strunk | Author | Elements of Style | 1869 | 1946 |
| | | Levi Stubbs | Singer | The Four Tops | 1936 | 2008 |
| | | Theodore Sturgeon | Author | More Than Human | 1918 | 1985 |
| | | John Sturges | Film Director | The Great Escape | 1911 | 1992 |
| | | Preston Sturges | Screenwriter | Sullivan's Travels | 1898 | 1959 |
| | | Jule Styne | Songwriter | Gypsy | 1905 | 1994 |
| | | William Styron | Novelist | The Confessions of Nat Turner | 1925 | 2006 |
| | | John Suckling | Poet | | 1609 | 1642 |
| | | Danny Sugerman | Author | Manager/Biographer for The Doors | 1954 | 2005 |
| | | Chiune Sugihara | Diplomat | Helped Jews escape Lithuania | 1900 | 1986 |
| | | Josef Suk | Composer | Serenade for Strings in E flat | 1874 | 1935 |
| | | Suleiman the Magnificent | Royalty | Ottoman Sultan, 1520-66 | 1494 | 1566 |
| | | Anne Sullivan | Educator | Teacher of Helen Keller | 1866 | 1936 |
| | | Arthur Sullivan | Composer | Gilbert & Sullivan | 1842 | 1900 |
| | | Ed Sullivan | TV Personality | The Ed Sullivan Show | 1901 | 1974 |
| | | Maxine Sullivan | Jazz Musician | American blues and jazz singer | 1911 | 1987 |
| | | Niki Sullivan | Guitarist | | 1937 | 2004 |
| |  | Yma Sumac | Singer | Vocalist with a 4.5-octave | 1924 | 2008 |
| | | Donna Summer | Singer | Disco Diva | 1948 | |
| | | Pat Summerall | Football | Sportscaster | 1930 | |
| | | Lawrence Summers | Economist | US Treasury Secretary, 1999-2001 | 1954 | |
| | | Marc Summers | Talk Show Host | Super Sloppy Double Dare | 1951 | |
| | | Edith Clara Summerskill | Doctor | | 1901 | 1980 |
| | | Jeremy Sumpter | Actor | Star of remade Peter Pan | 1989 | |
| | | Sun Tzu | Author | The Art of War | 0400 BC | 0320 BC |
| | | Billy Sunday | Religion | Baseball evangelist | 1862 | 1935 |
| | | Franz von Suppé | Composer | Light Cavalry Overture | 1819 | 1895 |
| | | Jacqueline Susann | Novelist | Valley of the Dolls | 1918 | 1974 |
| | | Ron Suskind | Journalist | The Price of Loyalty | 1959 | |
| | | Franz Xaver Sussmayr | Composer | | 1766 | 1803 |
| | | Edgar A. Suter | | | 0000 | |
| | | Donald Sutherland | Actor | The Dirty Dozen | 1935 | |
| | | Joan Sutherland | Singer | Operatic soprano | 1926 | |
| | | Frank Sutton | Actor | Sgt. Vince Carter on Gomer Pyle | 1923 | 1974 |
| | | Willie Sutton | Criminal | Bank Robber | 1901 | 1980 |
| | | Mena Suvari | Actor | American Beauty | 1979 | |
| | | Han Suyin | Author | A Many-Splendoured Thing | 1917 | |
| | | David Suzuki | Naturalist | Television nature host | 1936 | |
| | | Masaaki Suzuki | Conductor | | 1954 | |
| | | Shinichi Suzuki | Violinist | Suzuki method of music education | 1898 | 1998 |
| | | Shunryu Suzuki | Religion | | 1904 | 1971 |
| | | Johan Svendsen | Composer | Norwegian composer, conductor and violinist | 1840 | 1911 |
| | | Evgeny Svetlanov | Conductor | USSR State Symphony Orchestra | 1928 | 2002 |
| | | Jimmy Swaggart | Religion | Televangelist | 1935 | |
| | | Hilary Swank | Actor | Boys Don't Cry | 1974 | |
| | | Gloria Swanson | Actor | Sunset Blvd. | 1899 | 1983 |
| | | Kristy Swanson | Actor | Original Buffy the Vampire Slayer | 1969 | |
| | | John Cameron Swayze | Journalist | Camel News Caravan, Timex watch commercials | 1906 | 1995 |
| | | Patrick Swayze | Actor | Dirty Dancing | 1952 | |
| | | Keith Sweat | Singer | | 1961 | |
| | | Jan Pieterszoon Sweelinck | Composer | | 1562 | 1621 |
| | | D.B. Sweeney | Actor | Shoeless Joe in Eight Men Out | 1961 | |
| | | May Swenson | Playwright | | 1919 | 1989 |
| | | Jonathan Swift | Author | Gulliver's Travels | 1667 | 1745 |
| | | Taylor Swift | Country Musician | Teen country music sensation | 1989 | |
| | | Algernon Swinburne | Poet | | 1837 | 1909 |
| | | Tilda Swinton | Actor | The Deep End | 1960 | |
| | | Loretta Swit | Actor | Hot Lips on M*A*S*H | 1937 | |
| | | Barry Switzer | Football | Former Dallas Cowboys head coach | 1937 | |
| | | Herbert Bayard Swope | Editor | New York World newspaper | 1882 | 1958 |
| | | Sydney Pollack | Film Director | Out of Africa | 1934 | 2008 |
| | | Max von Sydow | Actor | The Exorcist | 1929 | |
| | | Eric Sykes | Actor | The Plank | 1923 | |
| | | John Millington Synge | Playwright | The Playboy of the Western World | 1871 | 1909 |
| | | Thomas Szasz | Author | Hungarian medical writer | 1920 | |
| | | George Szell | Conductor | | 1897 | 1970 |
| | | Albert Szent-Gyorgyi | Scientist | Vitamins C and B2 | 1893 | 1986 |
| | | Henryk Szeryng | Violinist | Violin virtuoso of Polish and Jewish heritage | 1918 | 1988 |
| | | Joseph Szigeti | Violinist | Hungarian virtuoso violinist | 1892 | 1973 |
| | | Leo Szilard | Physicist | | 1898 | 1964 |
| | | Karol Szymanowski | Composer | Polish composer and pianist | 1882 | 1937 |
| | | Harald Sćverud | Composer | Norwegian composer | 1897 | 1992 |
